The fearsome Brood have overtaken the orbital research satellite known as Pandora’s Box — stranding Beast’s girlfriend, S.W.O.R.D. agent Abigail Brand. Embarking on a daring rescue mission, Beast, Storm, Colossus, Kitty Pryde and Lockheed will encounter old friends and older enemies. But to escape the inescapable Pandora’s Box — commissioned to house hazardous experiments on the universe’s horrors — they must not only survive one of the most dangerous alien species in existence, but also make an impossible decision: Even if it means sparing untold lives, can the X-Men bring themselves to rescue the Brood along with their friends? Plus: a classic tale of the Brood by Chris Claremont and Dave Cockrum!

Collecting ASTONISHING X-MEN (2004) #38, #40, #42, #43 and UNCANNY X-MEN (1963) #162.